Radiation Therapy for Recurrent or Residual Pituitary Macroadenoma Invading Extrasellar Structures.

ABSTRACT:

Purpose

This study aimed to evaluate the efficacy of radiation therapy (RT) for recurrent or residual pituitary macroadenoma (PMA) invading extrasellar regions.

Materials and methods

Patients from 2000 to 2020 who received RT with conventional fractionation for recurrent or residual PMA were included. The patients were divided according to the type of tumor [functioning (fx) or non-fx] and the aim of RT (salvage RT alone, immediate postoperative RT, delayed postoperative RT). Local and biochemical failure-free rates (FFR) were calculated using the Kaplan-Meier method.

Results

With a median follow up of 82 months (IQR; 42-132 months), 36 patients treated with conventional RT (total 45-54 Gy in 1.8 or 2 Gy per fraction) for recurrent or residual PMA were analyzed. The 1

SUBMITTER: Kim K 

PROVIDER: S-EPMC9760886 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature