Growth inhibition of Trichophyton rubrum by laser irradiation: exploring further experimental aspects in an in vitro evaluation study.

ABSTRACT:

Background

According to the results of the clinical trials, laser therapy is effective for the treatment of onychomycosis, but the in vitro findings are inconsistent among studies. This study aimed to explore the experimental conditions of laser for the inhibition of Trichophyton rubrum growth in vitro. A 1064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser was used to irradiate colonies using a small (6-mm diameter) or large (13-mm diameter) area, and using 300, 408, or 600 J/cm². The surface temperature of the colony was measured after irradiation and every 2 min. The growth area was calculated until the 7th or 10th day of incubation daily.

Results

For the small area group, at 300 J/cm², the immediate surface temperature was 25.2 ± 0.2°C, bu

SUBMITTER: Zhang R 

PROVIDER: S-EPMC9762111 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature