Genetic Pathways Underlying Individual Differences in Regular Physical Activity.

ABSTRACT: Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs.

SUBMITTER: de Geus EJC 

PROVIDER: S-EPMC9762726 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature