Dataset Information

Unsupervised Learning Composite Network to Reduce Training Cost of Deep Learning Model for Colorectal Cancer Diagnosis.

ABSTRACT: Deep learning facilitates complex medical data analysis and is increasingly being explored in colorectal cancer diagnostics. However, the training cost of the deep learning model limits its real-world medical utility. In this study, we present a composite network that combines deep learning and unsupervised K-means clustering algorithm (RK-net) for automatic processing of medical images. RK-net was more efficient in image refinement compared with manual screening and annotation. The training of a deep learning model for colorectal cancer diagnosis was accelerated by two times with utilization of RK-net-processed images. Better performance was observed in training loss and accuracy achievement as well. RK-net could be useful to refine medical images of the ever-expanding quantity and assist in subsequent construction of the artificial intelligence model.

SUBMITTER: Guo J

PROVIDER: S-EPMC9762730 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Unsupervised Learning Composite Network to Reduce Training Cost of Deep Learning Model for Colorectal Cancer Diagnosis.

Guo Jirui J Cao Wuteng W Nie Bairun B Qin Qiyuan Q

IEEE journal of translational engineering in health and medicine 20221121

Deep learning facilitates complex medical data analysis and is increasingly being explored in colorectal cancer diagnostics. However, the training cost of the deep learning model limits its real-world medical utility. In this study, we present a composite network that combines deep learning and unsupervised K-means clustering algorithm (RK-net) for automatic processing of medical images. RK-net was more efficient in image refinement compared with manual screening and annotation. The training of ...[more]

PMID: 36544891

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Project description:Humans continuously categorise inputs, but only rarely receive explicit feedback as to whether or not they are correct. This implies that they may be integrating unsupervised information together with their sparse supervised data - a form of semi-supervised learning. However, experiments testing semi-supervised learning are rare, and are bedevilled with conflicting results about whether the unsupervised information affords any benefit. Here, we suggest that one important factor that has been paid insufficient attention is the alignment between subjects' internal representations of the stimulus material and the experimenter-defined representations that determine success in the tasks. Subjects' representations are shaped by prior biases and experience, and unsupervised learning can only be successful if the alignment suffices. Otherwise, unsupervised learning might harmfully strengthen incorrect assumptions. To test this hypothesis, we conducted an experiment in which subjects initially categorise items along a salient, but task-irrelevant, dimension, and only recover the correct categories when sufficient feedback draws their attention to the subtle, task-relevant, stimulus dimensions. By withdrawing feedback at different stages along this learning curve, we tested whether unsupervised learning improves or worsens performance when internal stimulus representations and task are sufficiently or insufficiently aligned, respectively. Our results demonstrate that unsupervised learning can indeed have opposing effects on subjects' learning. We also discuss factors limiting the degree to which such effects can be predicted from momentary performance. Our work implies that predicting and understanding human category learning in particular tasks requires assessment and consideration of the representational spaces that subjects entertain for the materials involved in those tasks. These considerations not only apply to studies in the lab, but could also help improve the design of tutoring systems and instruction.

Project description:PurposeImage quality of positron emission tomography (PET) is limited by various physical degradation factors. Our study aims to perform PET image denoising by utilizing prior information from the same patient. The proposed method is based on unsupervised deep learning, where no training pairs are needed.MethodsIn this method, the prior high-quality image from the patient was employed as the network input and the noisy PET image itself was treated as the training label. Constrained by the network structure and the prior image input, the network was trained to learn the intrinsic structure information from the noisy image and output a restored PET image. To validate the performance of the proposed method, a computer simulation study based on the BrainWeb phantom was first performed. A 68Ga-PRGD2 PET/CT dataset containing 10 patients and a 18F-FDG PET/MR dataset containing 30 patients were later on used for clinical data evaluation. The Gaussian, non-local mean (NLM) using CT/MR image as priors, BM4D, and Deep Decoder methods were included as reference methods. The contrast-to-noise ratio (CNR) improvements were used to rank different methods based on Wilcoxon signed-rank test.ResultsFor the simulation study, contrast recovery coefficient (CRC) vs. standard deviation (STD) curves showed that the proposed method achieved the best performance regarding the bias-variance tradeoff. For the clinical PET/CT dataset, the proposed method achieved the highest CNR improvement ratio (53.35% ± 21.78%), compared with the Gaussian (12.64% ± 6.15%, P = 0.002), NLM guided by CT (24.35% ± 16.30%, P = 0.002), BM4D (38.31% ± 20.26%, P = 0.002), and Deep Decoder (41.67% ± 22.28%, P = 0.002) methods. For the clinical PET/MR dataset, the CNR improvement ratio of the proposed method achieved 46.80% ± 25.23%, higher than the Gaussian (18.16% ± 10.02%, P < 0.0001), NLM guided by MR (25.36% ± 19.48%, P < 0.0001), BM4D (37.02% ± 21.38%, P < 0.0001), and Deep Decoder (30.03% ± 20.64%, P < 0.0001) methods. Restored images for all the datasets demonstrate that the proposed method can effectively smooth out the noise while recovering image details.ConclusionThe proposed unsupervised deep learning framework provides excellent image restoration effects, outperforming the Gaussian, NLM methods, BM4D, and Deep Decoder methods.

Dataset Information

Unsupervised Learning Composite Network to Reduce Training Cost of Deep Learning Model for Colorectal Cancer Diagnosis.

Publications

Unsupervised Learning Composite Network to Reduce Training Cost of Deep Learning Model for Colorectal Cancer Diagnosis.

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