Iron supplementation and the risk of bronchopulmonary dysplasia in extremely low gestational age newborns.

ABSTRACT:

Background

The aim of this study was to determine the relationship between iron exposure and the development of bronchopulmonary dysplasia (BPD).

Methods

A secondary analysis of the PENUT Trial dataset was conducted. The primary outcome was BPD at 36 weeks gestational age and primary exposures of interest were cumulative iron exposures in the first 28 days and through 36 weeks' gestation. Descriptive statistics were calculated for study cohort characteristics with analysis adjusted for the factors used to stratify randomization.

Results

Of the 941 patients, 821 (87.2%) survived to BPD evaluation at 36 weeks, with 332 (40.4%) diagnosed with BPD. The median cohort gestational age was 26 weeks and birth weight 810 g. In the first 28 days, 76% of infants received enteral

SUBMITTER: Garcia MR 

PROVIDER: S-EPMC9763546 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature