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Variation in human water turnover associated with environmental and lifestyle factors.


ABSTRACT: Water is essential for survival, but one in three individuals worldwide (2.2 billion people) lacks access to safe drinking water. Water intake requirements largely reflect water turnover (WT), the water used by the body each day. We investigated the determinants of human WT in 5604 people from the ages of 8 days to 96 years from 23 countries using isotope-tracking (2H) methods. Age, body size, and composition were significantly associated with WT, as were physical activity, athletic status, pregnancy, socioeconomic status, and environmental characteristics (latitude, altitude, air temperature, and humidity). People who lived in countries with a low human development index (HDI) had higher WT than people in high-HDI countries. On the basis of this extensive dataset, we provide equations to predict human WT in relation to anthropometric, economic, and environmental factors.

SUBMITTER: Yamada Y 

PROVIDER: S-EPMC9764345 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature

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Variation in human water turnover associated with environmental and lifestyle factors.

Yamada Yosuke Y   Zhang Xueying X   Henderson Mary E T MET   Sagayama Hiroyuki H   Pontzer Herman H   Watanabe Daiki D   Yoshida Tsukasa T   Kimura Misaka M   Ainslie Philip N PN   Andersen Lene F LF   Anderson Liam J LJ   Arab Lenore L   Baddou Issad I   Bedu-Addo Kweku K   Blaak Ellen E EE   Blanc Stephane S   Bonomi Alberto G AG   Bouten Carlijn V C CVC   Bovet Pascal P   Buchowski Maciej S MS   Butte Nancy F NF   Camps Stefan G SG   Close Graeme L GL   Cooper Jamie A JA   Cooper Richard R   Das Sai Krupa SK   Dugas Lara R LR   Eaton Simon S   Ekelund Ulf U   Entringer Sonja S   Forrester Terrence T   Fudge Barry W BW   Goris Annelies H AH   Gurven Michael M   Halsey Lewis G LG   Hambly Catherine C   El Hamdouchi Asmaa A   Hoos Marije B MB   Hu Sumei S   Joonas Noorjehan N   Joosen Annemiek M AM   Katzmarzyk Peter P   Kempen Kitty P KP   Kraus William E WE   Kriengsinyos Wantanee W   Kushner Robert F RF   Lambert Estelle V EV   Leonard William R WR   Lessan Nader N   Martin Corby K CK   Medin Anine C AC   Meijer Erwin P EP   Morehen James C JC   Morton James P JP   Neuhouser Marian L ML   Nicklas Theresa A TA   Ojiambo Robert M RM   Pietiläinen Kirsi H KH   Pitsiladis Yannis P YP   Plange-Rhule Jacob J   Plasqui Guy G   Prentice Ross L RL   Rabinovich Roberto A RA   Racette Susan B SB   Raichlen David A DA   Ravussin Eric E   Redman Leanne M LM   Reilly John J JJ   Reynolds Rebecca M RM   Roberts Susan B SB   Schuit Albertine J AJ   Sardinha Luis B LB   Silva Analiza M AM   Sjödin Anders M AM   Stice Eric E   Urlacher Samuel S SS   Valenti Giulio G   Van Etten Ludo M LM   Van Mil Edgar A EA   Wells Jonathan C K JCK   Wilson George G   Wood Brian M BM   Yanovski Jack A JA   Murphy-Alford Alexia J AJ   Loechl Cornelia U CU   Luke Amy H AH   Rood Jennifer J   Westerterp Klaas R KR   Wong William W WW   Miyachi Motohiko M   Schoeller Dale A DA   Speakman John R JR  

Science (New York, N.Y.) 20221124 6622


Water is essential for survival, but one in three individuals worldwide (2.2 billion people) lacks access to safe drinking water. Water intake requirements largely reflect water turnover (WT), the water used by the body each day. We investigated the determinants of human WT in 5604 people from the ages of 8 days to 96 years from 23 countries using isotope-tracking (<sup>2</sup>H) methods. Age, body size, and composition were significantly associated with WT, as were physical activity, athletic s  ...[more]

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