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ABSTRACT: Introduction
Pain is prevalent in people living with overweight and obesity. Obesity is associated with increased self-reported pain intensity and pain-related disability, reductions in physical functioning and poorer psychological well-being. People living with obesity tend to respond less well to pain treatments or management compared with people living without obesity. Mechanisms linking obesity and pain are complex and may include contributions from and interactions between physiological, behavioural, psychological, sociocultural, biomechanical and genetic factors. Our aim is to study the multidimensional pain profiles of people living with obesity, over time, in an attempt to better understand the relationship between obesity and pain.Methods and analysis
This longitudinal observational cohort study will recruit (n=216) people living with obesity and who are newly attending three weight management services in Ireland. Participants will complete questionnaires that assess their multidimensional biopsychosocial pain experience at baseline and at 3, 6, 12 and 18 months post-recruitment. Quantitative analyses will characterise the multidimensional pain experiences and trajectories of the cohort as a whole and in defined subgroups.Ethics and dissemination
The study protocol has been approved by the Ethics and Medical Research Committee of St Vincent's Healthcare Group, Dublin, Ireland (reference no: RS21-059) and the University College Dublin Human Research Ethics Committee (reference no: LS-E-22-41-Hinwood-Smart). Findings will be disseminated through peer-reviewed journals, conference presentations, public and patient advocacy groups, and social media.Study registration
Open Science Framework Registration DOI: https://doi.org/10.17605/OSF.IO/QCWUE.
SUBMITTER: Smart KM
PROVIDER: S-EPMC9764675 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
Smart Keith M KM Hinwood Natasha S NS Dunlevy Colin C Doody Catherine M CM Blake Catherine C Fullen Brona M BM Le Roux Carel W CW O'Connell Jean J Gilsenan Clare C Finucane Francis M FM O'Donoghue Grainne G
BMJ open 20221216 12
<h4>Introduction</h4>Pain is prevalent in people living with overweight and obesity. Obesity is associated with increased self-reported pain intensity and pain-related disability, reductions in physical functioning and poorer psychological well-being. People living with obesity tend to respond less well to pain treatments or management compared with people living without obesity. Mechanisms linking obesity and pain are complex and may include contributions from and interactions between physiolog ...[more]