The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants. The burden of RSV infection in healthy term infants has not yet been established. Accurate health-care burden data in healthy infants are necessary to determine RSV immunisation policy when RSV immunisation becomes available.

Methods

We performed a multicentre, prospective, observational birth cohort study in healthy term-born infants (≥37 weeks of gestation) in five sites located in different European countries to determine the health-care burden of RSV. The incidence of RSV-associated hospitalisations in the first year of life was determined by parental questionnaires and hospital chart reviews. We performed active RSV surveillance in a nested cohort to determine the incidence of m

SUBMITTER: Wildenbeest JG 

PROVIDER: S-EPMC9764871 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature