Comparative sequence analysis of SARS nCoV and SARS CoV genomes for variation in structural proteins

ABSTRACT: SARS-nCoV was identified as corona virus had spread worldwide very quickly and affected more than million people worldwide. To halt this acceleration and for efficient control the knowledge on genomic information is of utmost importance. We attempted to determine the nature of variation i.e., insertion, deletion, substitution, among structural sequences required to code for membrane, spike, nucleocapsid, envelope protein and glycosylation variation between SARS CoV and SARS nCoV spike glycoproteins, respectively. Comparative sequence analysis was performed by using retrieved sequences from the NCBI database. The analyzed sequences revealed, that the sequences coding for envelope protein show minor substituting amino acids. SARS CoV showed 94.74 percent amino acid identities with SARS nCoV

SUBMITTER: Sangwan J 

PROVIDER: S-EPMC9765352 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature