Painless and sensitive pepsinogen I detection: an electrochemical immunosensor based on rhombic dodecahedral Cu₃Pt and MoS₂ NFs.

ABSTRACT: Gastric cancer (GC) is a common malignant tumour of the digestive tract with a high mortality rate worldwide. However, many patients delay treatment due to the avoidance of the costly and painful procedure of gastroscopy. Therefore, an early convenient screening method is essential to improve the survival rate of GC patients. To address this issue, we constructed an electrochemical immunosensor supported by rhombohedral Cu₃Pt and MoS₂ nanoflowers (MoS₂ NFs) for rapid, painless and quantitative detection of the GC biomarker in vitro. Here, pepsinogen I was employed as a model protein biomarker to analyse the performance of the immunosensor. The rhombohedral dodecahedral Cu₃Pt nanoparticles decorated with MoS₂-NFs were further fun

SUBMITTER: Wei S 

PROVIDER: S-EPMC9765571 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature