A promising future for endometriosis diagnosis and therapy: extracellular vesicles - a systematic review.

ABSTRACT: Endometriosis is a chronic, inflammatory gynaecological disease that can have severe negative impacts on quality of life and fertility, placing burden on patients and the healthcare system. Due to the heterogeneous nature of endometriosis, and the lack of correlation between symptom and surgical disease severity, diagnosis and treatment remain a significant clinical challenge. Extracellular vesicles (EVs) are biologically active particles containing molecular cargo involved in intercellular communication, that can be exploited for diagnostic and therapeutic purposes.We systematically reviewed studies exploring EVs and their role in endometriosis, specifically addressing diagnostic and therapeutic potential and current understanding of pathophysiology. Five databases (Pubmed, Embase, Medlin

SUBMITTER: Scheck S 

PROVIDER: S-EPMC9768904 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature