Longitudinal assessment of maternal depression and early childhood asthma and wheeze: Effect modification by child sex.

ABSTRACT:

Background

Studies report associations between maternal mental health and adverse respiratory outcomes in children; however, the impact of timing and duration of maternal distress remains understudied. We sought to longitudinally examine associations between maternal depression and childhood asthma and wheeze, and explore sex differences.

Methods

Maternal depression (n = 601) was assessed using the Edinburgh Depression Scale questionnaire, dichotomized at a clinically relevant cutoff (>12) (a) during pregnancy, (b) postpartum, and (c) postpartum and subsequent time points postnatally (recurrent depression). Report of wheeze in the past 12 months (current wheeze) and asthma were obtained using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire

SUBMITTER: Alcala CS 

PROVIDER: S-EPMC9771993 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature