Sleep, cardiovascular risk factors, and kidney function: The Multi-Ethnic Study of Atherosclerosis (MESA).

ABSTRACT:

Objectives

Examine the associations of sleep measures with kidney function changes over time among individuals from a community-based study.

Methods

The sample includes 1657 participants (287 with chronic kidney disease [CKD]) in the Multi-Ethnic Study of Atherosclerosis Sleep Cohort (mean age: 57.7 years, male: 46.0%). We examined associations between a large set of sleep variables (polysomnography, actigraphy, and questionnaires) and cardiovascular disease risk factors and changes in estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio over approximately 5 years using high-dimensional regression. We investigated the modifying effect of sleep on the associations between cardiovascular disease risk factors and kidney function.

Results

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SUBMITTER: Chen J 

PROVIDER: S-EPMC9772248 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature