Dataset Information

Worldwide productivity and research trend of publications concerning glioma-associated macrophage/microglia: A bibliometric study.

ABSTRACT: Glioma-associated macrophage/microglia (GAM) represents a key player in shaping a unique glioma ecosystem to facilitate tumor progression and therapeutic resistance. Numerous studies have been published concerning GAM, but no relevant bibliometric study has been performed yet. Our bibliometric study aimed to comprehensively summarize and analyze the global scientific output, research hotspots, and trendy topics of publications on GAM over time. Data on publications on GAM were collected using the Web of Science (WoS). The search date was 16 January 2022, and the publications were collected from 2002 to 2021. Totally, 1,224 articles and reviews were incorporated and analyzed in the current study. It showed that the annual publications concerning GAM kept increasing over the past 20 years. The United States had the largest number of publications and total citations. Holland, Kettenmann, and Gutmann were the top three authors in terms of citation frequency. Neuro-oncology represented the most influential journal in GAM studies, with the highest H-index, total citations, and publication numbers. The paper published by Hambardzumyan in 2016 had the highest local citations. Additionally, the analysis of keywords implied that "prognosis," "tumor microenvironment," and "immunotherapy" might become research hotspots. Furthermore, trendy topics in GAM studies suggested that "immune infiltration," "immune microenvironment," "bioinformatics," "prognosis," and "immunotherapy" deserved additional attention. In conclusion, this bibliometric study comprehensively analyzed the publication trend of GAM studies for the past 20 years, in which the research hotspots and trendy topics were also uncovered. This information offered scholars critical references for conducting in-depth studies on GAM in the future.

SUBMITTER: Liu YY

PROVIDER: S-EPMC9772275 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Worldwide productivity and research trend of publications concerning glioma-associated macrophage/microglia: A bibliometric study.

Liu Yu-Yang YY Yao Ren-Qi RQ Long Li-Yan LY Liu Yu-Xiao YX Tao Bing-Yan BY Liu Hong-Yu HY Liu Jia-Lin JL Li Ze Z Chen Ling L Yao Yong-Ming YM

Frontiers in neurology 20221208

Glioma-associated macrophage/microglia (GAM) represents a key player in shaping a unique glioma ecosystem to facilitate tumor progression and therapeutic resistance. Numerous studies have been published concerning GAM, but no relevant bibliometric study has been performed yet. Our bibliometric study aimed to comprehensively summarize and analyze the global scientific output, research hotspots, and trendy topics of publications on GAM over time. Data on publications on GAM were collected using th ...[more]

PMID: 36570441

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Project description:BackgroundAs the complexity and diversity of the tumor immune microenvironment (TIME) are becoming better understood, burgeoning research has progressed in this field. However, there is a scarcity of literature specifically focused on the bibliometric analysis of this topic. This study sought to investigate the development pattern of TIME-related research from 2006 to September 14, 2022, from a bibliometric perspective.MethodsWe acquired both articles and reviews related to TIME from the Web of Science Core Collection (WoSCC) (retrieved on September 14, 2022). R package "Bibliometrix" was used to calculate the basic bibliometric features, present the collaborative conditions of countries and authors, and generate a three-field plot to show the relationships among authors, affiliations, and keywords. VOSviewer was utilized for co-authorship analysis of country and institution and keyword co-occurrence analysis. CiteSpace was used for citation burst analysis of keywords and cited references. In addition, Microsoft Office Excel 2019 was used to develop an exponential model to fit the cumulative publication numbers.ResultsA total of 2545 publications on TIME were included, and the annual publication trend exhibited a significant increase over time. China and Fudan University were the most productive country and institution, with the highest number of publications of 1495 and 396, respectively. Frontiers in Oncology held the highest number of publications. A number of authors were recognized as the main contributors in this field. The clustering analysis revealed six clusters of keywords that highlighted the research hot spots in the fields of basic medical research, immunotherapy, and various cancer types separately.ConclusionsThis research analyzed 16 years of TIME-related research and sketched out a basic knowledge framework that includes publications, countries, journals, authors, institutions, and keywords. The finding revealed that the current research hot spots of the TIME domain lie in "TIME and cancer prognosis", "cancer immunotherapy", and "immune checkpoint". Our researchers identified the following areas: "immune checkpoint-based immunotherapy", "precise immunotherapy" and "immunocyte pattern", which may emerge as frontiers and focal points in the upcoming years, offering valuable avenues for further exploration.

Project description:BackgroundThe influence of the pharmaceutical industry and other stakeholders on medical science has been increasingly criticised. When dealing with conflicts of interest in scientific publications it is important to ensure the best possible transparency. The objective of this work is to examine the disclosure practice of financial and non-financial conflicts of interest in German language publications concerning health services research for the first time.MethodsWe performed a systematic literature search in the PubMed data base using the MeSH term "health services research". The review was conducted on July 10, 2006, setting the limits "dates: published in the last 2 years" and "languages: German" (only articles with abstracts). 124 articles in 31 magazines were found. In the magazines the instructions for authors were examined as to whether a statement on conflicts of interest is expected--and if, in which form. Regarding the articles in the journals which require a statement, we examined whether the statement is explicitly published. The results are descriptively represented.Results13 magazines (42%) do not require any statement on conflicts of interest, whereas 18 journals (58%) expect a statement. Two of these 18 magazines refer explicitly to the uniform requirements of the International Committee of the Medical Journal Editors (ICMJE); the remaining 16 magazines give differently accentuated instructions on how to disclose conflicts of interest, whereby the focus is primarily on financial issues. A statement on conflicts of interest is explicitly published in 11 of the 71 articles (15%) which are found in the magazines that require a statement with the submission of a manuscript. Related to the total number of included articles, this means that the reader explicitly receives information on potential conflicts of interest in 9% of the cases (11 of 124 articles). Statements of others that are involved in the publication process (reviewers, editors) are not available in any of the articles examined.ConclusionA better sensitization for possible conflicts of interest in German publications concerning health services research is necessary. We suggest tightening the criteria for disclosure in the instructions for authors in the scientific journals. Among other things the equivalent consideration of financial and non-financial conflicts of interest as well as the obligatory publication of the statements should be part of good practice.

Project description:PurposeMedical research is a crucial indicator of a nation's reputation and development. However, there are concerns about the limited orthopedic research in Kingdom of Saudi Arabia (KSA). Therefore, this study conducted bibliometric analysis to investigate orthopedic research output from KSA.MethodsPubMed database for orthopedic articles, with a minimum of one KSA-affiliated orthopedic author published from the year 2000 onwards, was searched. This excluded duplicate articles, corrections, letters, editorials, commentaries, and brief communications. The titles of the included articles, publication years, first and corresponding authors' primary affiliations and countries, countries and institutes of research, and total citations were noted. Thereafter, year-wise research contribution, top contributing and collaborating nations, top contributing affiliations, study types, levels of evidence, journal distribution, their impact factor, h-index and quartile-related information, and citation trends were analyzed.ResultsThe search strategy yielded 1047 eligible articles. An increasing trend in research contributions in recent years was observed, with the least number of articles (8) contributed in 2005 and the most (140) in 2023. The research was conducted in KSA for most articles (83.48%). Authors from Canada collaborated in 3.44% of the articles. King Saud University was the top contributing institution (17.38% of all articles). There were 66 (6.30%) basic science studies and 873 (83.3%) clinical studies. Among non-basic science studies, 84.51% had level IV evidence. Overall, 73.83% of articles had either first/corresponding or both authorships from KSA-affiliated orthopedic authors. The eligible articles were published in 303 journals, with a mean impact factor of 3.04 (range 0.4-51.1, 165 journals) and a mean h-index of 59.2 (range 1-367, 277 journals). Overall, 31.23% of articles with quartile information available were published in first-quartile journals.ConclusionsThe orthopedic research productivity in KSA is limited. However, there has been an increasing trend in orthopedic research in recent years. Nevertheless, the quality of clinical research, particularly the level of evidence, needs improvement. Therefore, further efforts should be made to strengthen research opportunities and encourage research participation among orthopedic and medical institutes.

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Worldwide productivity and research trend of publications concerning glioma-associated macrophage/microglia: A bibliometric study.

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Worldwide productivity and research trend of publications concerning glioma-associated macrophage/microglia: A bibliometric study.

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