In-process real-time probiotic phenotypic strain identity tracking: The use of Fourier transform infrared spectroscopy.

ABSTRACT: Probiotic bacteria, capable of conferring benefits to the host, can present challenges in design, development, scale-up, manufacturing, commercialization, and life cycle management. Strain identification is one of the main quality parameters; nevertheless, this task can be challenging since established methodologies can lack resolution at the strain level for some microorganisms and\or are labor-intensive and time-consuming. Fourier transform infrared spectroscopy (FTIRS) has been largely used for the investigation of pathogenic species in the clinical field, whereas only recently has been proposed for the identification of probiotic strains. Within the probiotic industrial production, bacterial strains can be subjected to stressful conditions that may affect genomic and phenotypic charact

SUBMITTER: Deidda F 

PROVIDER: S-EPMC9772554 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature