Treatment Preference Among People With Cystic Fibrosis: The Importance of Reducing Treatment Burden.

ABSTRACT:

Background

There is a growing consensus that the perspective of the patient should be considered in the evaluation of novel interventions.

Research question

What treatment outcomes matter to people with cystic fibrosis (CF), and what trade-offs would they make to realize these outcomes?

Study design and methods

Adults attending a specialist CF center were invited to complete an online discrete choice experiment (DCE). The DCE required participants to evaluate hypothetical CF treatment profiles, defined by impact on lung function, pulmonary exacerbations, abdominal symptoms, life expectancy, quality of life, inhaled medicine usage, and physiotherapy requirement. Choice data were analyzed, using multinomial logit and latent class models.

Results

One hundred and t

SUBMITTER: Cameron RA 

PROVIDER: S-EPMC9773229 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature