Prognostic value of CD8⁺ tumor-infiltrating T cells in patients with breast cancer: A systematic review and meta-analysis.

ABSTRACT: CD8⁺ tumor-infiltrating lymphocytes have been regarded as potential biomarkers for cancer prognosis, while the prognostic effect of CD8⁺ tumor-infiltrating T cells remains controversial in breast cancer. In the present study, a meta-analysis was performed to evaluate the prognostic value of CD8⁺ T cells in breast cancer and the associations between CD8⁺ T cells and the pathological characteristics. The PubMed, Embase and the Cochrane Library were systematically searched entries added from the establishment of the database to November 2021 and prospective or retrospective studies of patients with breast cancer were included. The Newcastle-Ottawa Scale was used to assess the quality of evidence for each study. STATA 15.1 was used for the data analy

SUBMITTER: Sun YP 

PROVIDER: S-EPMC9773320 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature