Bleeding in neonates with severe thrombocytopenia: a retrospective cohort study.

ABSTRACT:

Background

Severe neonatal thrombocytopenia is a rare disease with multiple etiologies. Severe thrombocytopenia with bleeding is life-threatening and has attracted significant attention from clinicians. However, only a few studies have focused on the association between severe thrombocytopenia and bleeding. Thus, this study aimed to describe the neonates' postnatal age at which severe thrombocytopenia was first recognized, clinical characteristics, bleeding patterns, and outcomes and to evaluate the association between minimum platelet count and bleeding.

Methods

A single-center retrospective cohort study for neonates with severe thrombocytopenia (platelet count ≤ 50 × 10⁹/L) was conducted. Neonates who were admitted to our neonatal intensive care unit between Oct

SUBMITTER: Peng T 

PROVIDER: S-EPMC9773444 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature