Large-scale genomic and transcriptomic profiles of rice hybrids reveal a core mechanism underlying heterosis.

ABSTRACT:

Background

Heterosis is widely used in agriculture. However, its molecular mechanisms are still unclear in plants. Here, we develop, sequence, and record the phenotypes of 418 hybrids from crosses between two testers and 265 rice varieties from a mini-core collection.

Results

Phenotypic analysis shows that heterosis is dependent on genetic backgrounds and environments. By genome-wide association study of 418 hybrids and their parents, we find that nonadditive QTLs are the main genetic contributors to heterosis. We show that nonadditive QTLs are more sensitive to the genetic background and environment than additive ones. Further simulations and experimental analysis support a novel mechanism, homo-insufficiency under insufficient background (HoIIB), underlying heterosis. We p

SUBMITTER: Xie J 

PROVIDER: S-EPMC9773586 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature