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ABSTRACT: Introduction
Reduced activity and sleep-wake rhythm disturbances are essential features of depressive episodes. In addition, alterations in heart rate variability (HRV) have been implicated in depression. By using a wearable sensor that monitors 3-dimensional acceleration and HRV simultaneously, we examined the activity and HRV indices in depressive episode of mood disorders.Methods
Participants were 19 patients (13 major depressive disorder [MDD] and 6 bipolar depression; 11 females) and 18 controls (9 females) matched for age and ethnicity (all Japanese) who completed 3 consecutive days of all-day monitoring by a small and light device attached to the chest.Results
Activity magnitude was significantly reduced while lying/resting time was increased in depressed pat
SUBMITTER: Koga N
PROVIDER: S-EPMC9773773 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature