Associations between serum soluble transferrin receptor and the prevalence of cancers.

ABSTRACT:

Background

As increasing experimental evidence suggests that iron metabolism play crucial roles in cancer and non-cancer conditions, there is a lack of data on serum soluble transferrin receptor (sTfR), a promising marker representing unmet cellular iron demands, between cancer risk from epidemiological studies. Here, we aimed to evaluate the predictive value of sTfR and cancer prevalence.

Materials and methods

We analyzed on 5,480 adult participants from 2015 to 2018 National Health and Nutrition Examination Survey (NHANES). Spearman correlation analysis was performed to investigate the correlations between sTfR and other characteristics. To identify the associations between sTfR and the prevalence of cancers, stratified multivariable logistic regression models, subgroup an

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9773974 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature