Systemic Antibiotics as an Adjunct to Subgingival Debridement: A Network Meta-Analysis.

ABSTRACT: This review aimed to evaluate the effectiveness of systemic antibiotics as adjunctive treatment to subgingival debridement in patients with periodontitis. Randomized controlled trials were included that assessed the effectiveness of systemic antibiotics in improving periodontal status, indicated by clinical attachment gain level, probable pocket depth reduction, and bleeding on probing reduction of patients with any form of periodontitis at any follow-up time. Network meta-analyses with a frequentist model using random effects was employed to synthesize the data. The relative effects were reported as mean difference with a 95% confidence interval. Subsequently, all treatments were ranked based on their P-scores. A total of 30 randomized controlled trials were included in this network meta-

SUBMITTER: Kherul Anuwar AH 

PROVIDER: S-EPMC9774554 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature