Effects of the Myokine Irisin on Stromal Cells from Swine Adipose Tissue.

ABSTRACT: Irisin is a hormone able to reproduce some of the positive effects of physical activity and diet. Recently, we demonstrated the presence of Irisin at the ovarian level as a potential physiological regulator of follicular function. Adipose tissue is crucial for reproductive function through its metabolic activity and the production of adipokines. At present, the exact nature of adipocyte precursors is still under debate, but an important role has been assigned to the population of adipose tissue mesenchymal stromal cells (ASCs) of perivascular origin. It should be noted that, when appropriately stimulated, ASCs can differentiate into preadipocytes and, subsequently, adipocytes. Therefore, this present study was undertaken to explore the potential effect of Irisin on ASCs, known for their hi

SUBMITTER: Basini G 

PROVIDER: S-EPMC9775982 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature