Unsaturated Fatty Acids in Mental Disorders: An Umbrella Review of Meta-Analyses.

ABSTRACT: Unsaturated fatty acids might be involved in the prevention of and improvement in mental disorders, but the evidence on these associations has not been comprehensively assessed. This umbrella review aimed to appraise the credibility of published evidence evaluating the associations between unsaturated fatty acids and mental disorders. In this umbrella review, systematic reviews and meta-analyses of studies comparing unsaturated fatty acids (including supplementation, dietary intake, and blood concentrations) in participants with mental disorders with healthy individuals were included. We reanalyzed summary estimates, between-study heterogeneity, predictive intervals, publication bias, small-study effects, and excess significance bias for each meta-analysis. Ninety-five meta-analyses from 2

SUBMITTER: Gao X 

PROVIDER: S-EPMC9776730 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature