Preoperative Radio(Chemo)Therapy in Breast Cancer: Time to Switch the Perspective?

ABSTRACT:

Aim

Radiation therapy represents, together with surgery and systemic treatment, the triad on which the current management of patients with breast cancer is based, achieving high control and survival rates. In recent years we have witnessed a (r)evolution in the conception of breast cancer treatment. The classic scheme of surgery followed by systemic treatment and radiotherapy is being subverted and it is becoming more and more frequent to propose the primary administration of systemic treatment before surgery, seeking to maximize its effect and favoring not only the performance of more conservative surgeries but also, in selected cases, increasing the rates of disease-free survival and overall survival. Radiotherapy is also evolving toward a change in perspective: considering preop

SUBMITTER: Montero A 

PROVIDER: S-EPMC9777182 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature