A Meta-Analysis of Observational Studies on Prolactin Levels in Women with Polycystic Ovary Syndrome.

ABSTRACT: Women with polycystic ovary syndrome (PCOS) are reported to have different levels of prolactin (PRL) compared to women without PCOS. This study aimed to evaluate the PRL levels in women with PCOS, compared to the control group, before and after adjustment for potential confounders. Using a logical combination of keywords, a comprehensive search was carried out in PubMed and Web of Science, from inception to 30 August 2022. Weighted mean differences (WMDs) with corresponding 95% CIs in PRL levels were employed with a random-effects model. I² was applied to evaluate heterogeneity among studies. A meta-regression analysis and subgroup analysis were conducted to explore heterogeneity sources. Publication bias was assessed by the Egger test. Thirty-two studies, measuring PRL levels i

SUBMITTER: Saei Ghare Naz M 

PROVIDER: S-EPMC9777544 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature