Polypharmacy Patterns in Multimorbid Older People with Cardiovascular Disease: Longitudinal Study.

ABSTRACT: (1) Introduction: Cardiovascular disease is associated with high mortality, especially in older people. This study aimed to characterize the evolution of combined multimorbidity and polypharmacy patterns in older people with different cardiovascular disease profiles. (2) Material and methods: This longitudinal study drew data from the Information System for Research in Primary Care in people aged 65 to 99 years with profiles of cardiovascular multimorbidity. Combined patterns of multimorbidity and polypharmacy were analysed using fuzzy c-means clustering techniques and hidden Markov models. The prevalence, observed/expected ratio, and exclusivity of chronic diseases and/or groups of these with the corresponding medication were described. (3) Results: The study included 114,516 people, most

SUBMITTER: Villen N 

PROVIDER: S-EPMC9777651 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature