The Expansion of the Spectrum in Stuttering Disorders to a Novel ARMC Gene Family (ARMC3).

ABSTRACT: Stuttering is a common neurodevelopment speech disorder that negatively affects the socio-psychological dimensions of people with disability. It displays many attributes of a complex genetic trait, and a few genetic loci have been identified through linkage studies. Stuttering is highly variable regarding its phenotypes and molecular etiology. However, all stutters have some common features, including blocks in speech, prolongation, and repetition of sounds, syllables, and words. The involuntary actions associated with stuttering often involve increased eye blinking, tremors of the lips or jaws, head jerks, clenched fists, perspiration, and cardiovascular changes. In the present study, we recruited a consanguineous Pakistani family showing an autosomal recessive mode of inheritance. The ex

SUBMITTER: Rehman AU 

PROVIDER: S-EPMC9778410 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature