Molecular evolution and signatures of selective pressures on Bos, focusing on the Nelore breed (Bos indicus).

ABSTRACT: Evolutionary history leads to genome changes over time, especially for species that have experienced intense selective pressures over a short period. Here, we investigated the genomic evolution of Bos species by searching for potential selection signatures, focusing on Nelore, an economically relevant cattle breed in Brazil. We assessed the genomic processes determining the molecular evolution across Nelore and thirteen other related taxa by evaluating (i) amino acid sequence conservation, (ii) the dN/dS ratio, and (iii) gene families' turnover rate (λ). Low conserved regions potentially associated with fatty acid metabolism seem to reflect differences in meat fat content in taxa with different evolutionary histories. All Bos species presented genes under positive selection, especially B.

SUBMITTER: Cortez T 

PROVIDER: S-EPMC9778527 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature