Improved pre-test likelihood estimation of coronary artery disease using phonocardiography.

ABSTRACT:

Aims

Current early risk stratification of coronary artery disease (CAD) consists of pre-test probability scoring such as the 2019 ESC guidelines on chronic coronary syndromes (ESC2019), which has low specificity and thus rule-out capacity. A newer clinical risk factor model (risk factor-weighted clinical likelihood, RF-CL) showed significantly improved rule-out capacity over the ESC2019 model. The aim of the current study was to investigate if the addition of acoustic features to the RF-CL model could improve the rule-out potential of the best performing clinical risk factor models.

Methods and results

Four studies with heart sound recordings from 2222 patients were pooled and distributed into two data sets: training and test. From a feature bank of 40 acoustic features, a f

SUBMITTER: Larsen BS 

PROVIDER: S-EPMC9779903 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature