Does repeated influenza vaccination attenuate effectiveness? A systematic review and meta-analysis.

ABSTRACT:

Background

Influenza vaccines require annual readministration; however, several reports have suggested that repeated vaccination might attenuate the vaccine's effectiveness. We aimed to estimate the reduction in vaccine effectiveness associated with repeated influenza vaccination.

Methods

In this systematic review and meta-analysis, we searched MEDLINE, EMBASE, and CINAHL Complete databases for articles published from Jan 1, 2016, to June 13, 2022, and Web of Science for studies published from database inception to June 13, 2022. For studies published before Jan 1, 2016, we consulted published systematic reviews. Two reviewers (EJ-G and EJR) independently screened, extracted data using a data collection form, assessed studies' risk of bias using the Risk Of Bias In Non-Rando

SUBMITTER: Jones-Gray E 

PROVIDER: S-EPMC9780123 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature