Effect of Long-term Exercise Training on Physical Performance and Cardiorespiratory Function in Adults With CKD: A Randomized Controlled Trial.

ABSTRACT:

Rationale & objective

The safety and efficacy of long-term exercise training in reducing physical functional loss in older adults with advanced CKD and comorbidity is uncertain.

Study design

Multicenter, parallel group, randomized controlled trial.

Settings & participants

Adults 55 years and older with estimated glomerular filtration rate (eGFR) of 15 to <45 mL/min/1.73 m² enrolled from centers in Baltimore and Boston.

Intervention

Twelve months of in-center supervised exercise training incorporating majority aerobic but also muscle strengthening activities or a group health education control intervention, randomly assigned in 1:1 ratio.

Outcome

Primary outcomes were cardiorespiratory fitness and submaximal gait at 6 and 12 months quantified b

SUBMITTER: Weiner DE 

PROVIDER: S-EPMC9780154 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature