Rare diseases and space health: optimizing synergies from scientific questions to care.

ABSTRACT: Knowledge transfer among research disciplines can lead to substantial research progress. At first glance, astronaut health and rare diseases may be seen as having little common ground for such an exchange. However, deleterious health conditions linked to human space exploration may well be considered as a narrow sub-category of rare diseases. Here, we compare and contrast research and healthcare in the contexts of rare diseases and space health and identify common barriers and avenues of improvement. The prevalent genetic basis of most rare disorders contrasts sharply with the occupational considerations required to sustain human health in space. Nevertheless small sample sizes and large knowledge gaps in natural history are examples of the parallel challenges for research and clinical car

SUBMITTER: Puscas M 

PROVIDER: S-EPMC9780351 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature