Derivation and validation of a clinical decision rule to risk-stratify COVID-19 patients discharged from the emergency department: The CCEDRRN COVID discharge score.

ABSTRACT:

Objective

To risk-stratify COVID-19 patients being considered for discharge from the emergency department (ED).

Methods

We conducted an observational study to derive and validate a clinical decision rule to identify COVID-19 patients at risk for hospital admission or death within 72 hours of ED discharge. We used data from 49 sites in the Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) between March 1, 2020, and September 8, 2021. We randomly assigned hospitals to derivation or validation and prespecified clinical variables as candidate predictors. We used logistic regression to develop the score in a derivation cohort and examined its performance in predicting short-term adverse outcomes in a validation cohort.

Results

Of 15,305 eligible patie

SUBMITTER: Brooks SC 

PROVIDER: S-EPMC9780419 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature