Emergence and Dissemination of Extraintestinal Pathogenic High-Risk International Clones of Escherichia coli.

ABSTRACT: Multiresistant Escherichia coli has been disseminated worldwide, and it is one of the major causative agents of nosocomial infections. E. coli has a remarkable and complex genomic plasticity for taking up and accumulating genetic elements; thus, multiresistant high-risk clones can evolve. In this review, we summarise all available data about internationally disseminated extraintestinal pathogenic high-risk E. coli clones based on whole-genome sequence (WGS) data and confirmed outbreaks. Based on genetic markers, E. coli is clustered into eight phylogenetic groups. Nowadays, the E. coli ST131 clone from phylogenetic group B2 is the predominant high-risk clone worldwide. Currently, strains of the C1-M27 subclade within clade C of ST131 are circulating and b

SUBMITTER: Kocsis B 

PROVIDER: S-EPMC9780897 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature