<i>Aggregatibacter actinomycetemcomitans</i> and <i>Filifactor alocis</i> as Associated with Periodontal Attachment Loss in a Cohort of Ghanaian Adolescents.

ABSTRACT: The aims of the present study were to document the presence of Aggregatibacter actinomyctemcomitans and the emerging oral pathogen Filifactor alocis, as well as to identify genotypes of these bacterial species with enhanced virulence. In addition, these data were analyzed in relation to periodontal pocket depth (PPD) and the progression of PPD from the sampled periodontal sites during a two-year period. Subgingival plaque samples were collected from 172 periodontal pockets of 68 Ghanaian adolescents. PPD at sampling varied from 3-14 mm and the progression from baseline, i.e., two years earlier up to 8 mm. The levels of A. actinomycetemcomitans and F. alocis were determined with quantitative PCR. The highly leukotoxic JP2-genotype of A. actinomycetemcomitans</

SUBMITTER: Razooqi Z 

PROVIDER: S-EPMC9781193 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature