Epidemiology and Genotype Distribution of Hepatitis C Virus in Russia.

ABSTRACT: The hepatitis C virus (HCV) causes both acute and chronic infection of the liver that can lead to liver cirrhosis, cancer, and liver failure. HCV is characterized by high genetic diversity and substantial variations in the prevalence of specific HCV genotypes throughout the world. Many effective regimens of direct-acting antivirals (DAAs), including pan-genotypic, can successfully treat HCV infection. Additionally, genotype-specific treatments for HCV are being actively employed in national plans for eliminating HCV infection around the world. The evaluation of HCV genotype prevalence in a given country is necessary for the successful implementation of the HCV elimination plans and for allocating financial resources to the DAAs which are the most effective against those specific HCV genoty

SUBMITTER: Pimenov N 

PROVIDER: S-EPMC9781887 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature