Divergent Contribution of the Golgi Apparatus to Microtubule Organization in Related Cell Lines.

ABSTRACT: Membrane trafficking in interphase animal cells is accomplished mostly along the microtubules. Microtubules are often organized radially by the microtubule-organizing center to coordinate intracellular transport. Along with the centrosome, the Golgi often serves as a microtubule-organizing center, capable of nucleating and retaining microtubules. Recent studies revealed the role of a special subset of Golgi-derived microtubules, which facilitates vesicular traffic from this central transport hub of the cell. However, proteins essential for microtubule organization onto the Golgi might be differentially expressed in different cell lines, while many potential participants remain undiscovered. In the current work, we analyzed the involvement of the Golgi complex in microtubule organization in

SUBMITTER: Brodsky IB 

PROVIDER: S-EPMC9782006 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature