Genomic Epidemiology of SARS-CoV-2 in Western Burkina Faso, West Africa.

ABSTRACT:

Background

After its initial detection in Wuhan, China, in December 2019, SARS-CoV-2 has spread rapidly, causing successive epidemic waves worldwide. This study aims to provide a genomic epidemiology of SARS-CoV-2 in Burkina Faso.

Methods

Three hundred and seventy-seven SARS-CoV-2 genomes obtained from PCR-positive nasopharyngeal samples (PCR cycle threshold score < 35) collected between 5 May 2020, and 31 January 2022 were analyzed. Genomic sequences were assigned to phylogenetic clades using NextClade and to Pango lineages using pangolin. Phylogenetic and phylogeographic analyses were performed to determine the geographical sources and time of virus introduction in Burkina Faso.

Results

The analyzed SARS-CoV-2 genomes can be assigned to 10 phylogenetic clades and 27

SUBMITTER: Sawadogo Y 

PROVIDER: S-EPMC9782145 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature