Magnetite Nanoparticles as Solar Photo-Fenton Catalysts for the Degradation of the 5-Fluorouracil Cytostatic Drug.

ABSTRACT: Heterogeneous catalysts based on magnetite nanoparticles, Fe₃O₄, were prepared by the chemical coprecipitation method using iron (III) chloride as a salt precursor. The physicochemical properties of the nanoparticles were determined by different techniques and the efficiency was evaluated for the degradation of the cytostatic drug, 5-fluorouracil (5-FU), in aqueous solution by photo-Fenton process under simulated solar radiation. The most influential parameters, namely pH of the solution, catalyst load, H₂O₂ dosage, and use of radiation, were studied and optimized in the degradation process. The optimal conditions to achieve a 100% degradation of 5-FU (10 mg L^-1) and a high mineralization degree (76%) were established at the acidic pH

SUBMITTER: Perez-Poyatos LT 

PROVIDER: S-EPMC9782202 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature