Genotoxic and Toxic Effects of The Flame Retardant Tris(Chloropropyl) Phosphate (TCPP) in Human Lymphocytes, Microalgae and Bacteria.

ABSTRACT: Tris(chloropropyl) phosphate (TCPP) is a characteristic and widely used organophosphorus flame retardant. TCPP is comprised of four isomers and the most abundant is tris(1-chloro-2-propyl) phosphate. TCPP can be released into the environment, with potential impacts on living organisms and humans due to its extensive industrial use. Aiming to assess the potential risks of TCPP on human health and the environment, its toxic and genotoxic effects-using organisms from different trophic levels, i.e., bacteria, green microalgae, and human cells-were investigated. TCPP exposure at nominal concentrations of 10, 20, 30 and 40 μg mL^-1 was studied to identify the potential risk of inducing genotoxic effects in cultured human lymphocytes. Treatment with 30 and 40 μg mL^-1 of TCPP

SUBMITTER: Antonopoulou M 

PROVIDER: S-EPMC9782401 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature