A First-Tier Framework for Assessing Toxicological Risk from Vaporized Cannabis Concentrates.

ABSTRACT: Vaporization is an increasingly prevalent means to consume cannabis, but there is little guidance for manufacturers or regulators to evaluate additive safety. This paper presents a first-tier framework for regulators and cannabis manufacturers without significant toxicological expertise to conduct risk assessments and prioritize additives in cannabis concentrates for acceptance, elimination, or further evaluation. Cannabinoids and contaminants (e.g., solvents, pesticides, etc.) are excluded from this framework because of the complexity involved in their assessment; theirs would not be a first-tier toxicological assessment. Further, several U.S. state regulators have provided guidance for major cannabinoids and contaminants. Toxicological risk assessment of cannabis concentrate additives, l

SUBMITTER: Vreeke S 

PROVIDER: S-EPMC9782653 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature