CXCL9-11 chemokines and CXCR3 receptor in teleost fish species.

ABSTRACT: The coordinated migration of immune cells from lymphoid organs to in or out of the bloodstream, and towards the site of infection or tissue damage is fundamental for an efficient innate and adaptive immune response. Interestingly, an essential part of this movement is mediated by chemoattractant cytokines called chemokines. Although the nature and function of chemokines and their receptors are well documented in mammals, much research is needed to accomplish a similar level of understanding of the role of chemokines in fish immunity. The first chemokine gene identified in teleosts (rainbow trout, Oncorhynchus mykiss) was CK1 in 1998. Since then, the identification of fish chemokine orthologue genes and characterization of their role has been more complex than expected, primarily bec

SUBMITTER: Valdes N 

PROVIDER: S-EPMC9782732 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature