Crystalloids vs. colloids for fluid optimization in patients undergoing brain tumour surgery.

ABSTRACT:

Background

This randomised, double-blinded, single-centre study prospectively investigated the impact of goal directed therapy and fluid optimization with crystalloids or colloids on perioperative complications in patients undergoing brain tumour surgery. Main aim of the study was to investigate the impact of fluid type on postoperative complications.

Patients and methods

80 patients were allocated into two equal groups to be optimised with either crystalloids (n = 40) or colloids (n = 40). Invasive hemodynamic monitoring was used to adjust and maintain mean arterial pressure and cerebral oxygenation within the baseline values (± 20%) and stroke volume variation (SVV) ≤ 10%. Postoperative complications from different organ systems were monitored during the first 15 days afte

SUBMITTER: Markovic-Bozic J 

PROVIDER: S-EPMC9784374 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature