Continuous Particle Aggregation and Separation in Acoustofluidic Microchannels Driven by Standing Lamb Waves.

ABSTRACT: In this study, we realize acoustic aggregation and separation of microparticles in fluid channels driven by standing Lamb waves of a 300-μm-thick double-side polished lithium-niobate (LiNbO₃) plate. We demonstrate that the counter-propagating lowest-order antisymmetric and symmetric Lamb modes can be excited by double interdigitated transducers on the LiNbO₃ plate to produce interfacial coupling with the fluid in channels. Consequently, the solid-fluid coupling generates radiative acoustic pressure and streaming fields to actuate controlled acoustophoretic motion of particles by means of acoustic radiation and Stokes drag forces. We conducted finite-element simulations based on the acoustic perturbation theory with full-wave modeling to tailor the acoustic and streami

SUBMITTER: Hsu JC 

PROVIDER: S-EPMC9785487 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature