Stability of Non-Ionic Surfactant Vesicles Loaded with Rifamycin S.

ABSTRACT: These days, the eradication of bacterial infections is more difficult due to the mechanism of resistance that bacteria have developed towards traditional antibiotics. One of the medical strategies used against bacteria is the therapy with drug delivery systems. Non-ionic vesicles are nanomaterials with good characteristics for encapsulating drugs, due to their bioavailability and biodegradability, which allow the drugs to reach the specific target and reduce their side effects. In this work, the antibiotic Rifamycin S was encapsulated. The rifamycin antibiotics family has been widely used against Mycobacterium tuberculosis, but recent studies have also shown that rifamycin S and rifampicin derivatives have bactericidal activity against Staphylococcus epidermidis and Staphy

SUBMITTER: Marchiano V 

PROVIDER: S-EPMC9785864 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature