Sex steroids and sex steroid-binding globulin levels amongst middle-aged and elderly men and women from general population.

ABSTRACT:

Background and aims

Availability of age- and sex-specific reference values for sex steroids and sex steroid-binding globulin (SHBG) levels allows for appropriate interpretation of research findings and their clinical applications. We report the sex-specific distribution and reference levels of sex steroids, including total estradiol, total testosterone and (calculated) free androgen index (cFAI), SHBG and other androgens dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulphate (DHEAS) and androstenedione across age.

Methods

Using data from 3291 participants from the prospective population-based Rotterdam Study (2006-2008), we visualised the distribution of sex steroids and SHBG levels by calculating and depicting the 5th, 25th, 50th, 75th and 95th percentiles per year

SUBMITTER: Aribas E 

PROVIDER: S-EPMC9787498 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature