Uric acid versus metabolic syndrome as markers of fatty liver disease in young people with overweight/obesity.

ABSTRACT:

Aims

To compare the association of high serum uric acid (HUA) or metabolic syndrome (MetS) with fatty liver disease (FLD) in youths with overweight/obesity (OW/OB).

Materials and methods

Cross-sectional study of anthropometrics, biochemical variables, and liver ultrasound of 3104 individuals with OW/OB (age 5-17 years). Metabolic syndrome was defined by ≥ 3 criteria among (1) high waist circumference; (2) high triglycerides; (3) low high-density lipoproteins; (4) fasting glucose ≥100 mg/dl; (5) blood pressure ≥95^th percentile in children, and ≥130/80 mmHg in adolescents. High serum uric acid was defined as serum UA value ≥ 75^th percentile adjusted for sex. Fatty liver disease was determined by echography.

Results

The sample was stratified in four

SUBMITTER: Di Bonito P 

PROVIDER: S-EPMC9787784 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature