Inhibitory Potential of Chromene Derivatives on Structural and Non-Structural Proteins of Dengue Virus.

ABSTRACT: Dengue fever is a mosquito-borne viral disease that has become a serious health issue across the globe. It is caused by a virus of the Flaviviridae family, and it comprises five different serotypes (DENV-1 to DENV-5). As there is no specific medicine or effective vaccine for controlling dengue fever, there is an urgent need to develop potential inhibitors against it. Traditionally, various natural products have been used to manage dengue fever and its co-morbid conditions. A detailed analysis of these plants revealed the presence of various chromene derivatives as the major phytochemicals. Inspired by these observations, authors have critically analyzed the anti-dengue virus potential of various 4H chromene derivatives. Further, in silico, in vitro, and in vivo reports of these scaf

SUBMITTER: Dharmapalan BT 

PROVIDER: S-EPMC9787897 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature