In Vitro Anti-Influenza Virus Activity of Non-Polar Primula veris subsp. veris Extract.

ABSTRACT: Medicinal plants have long been recognized as a tremendous source of candidate compounds for the development of pharmaceuticals, including anti-viral agents. Herein, we report the identification of anti-influenza virus activity in non-polar Primula veris L. subsp. veris extracts. We show that P. veris subsp. veris flower extracts, obtained using supercritical fluid or ultrasound-based extraction, possess virucidal/virus inactivation properties and confer prophylactic and therapeutic effects against influenza virus-induced cytolysis in vitro. By GC-MS and UPLC-HRMS analysis of non-polar P. veris subsp. veris extracts we identified terpenes, flavones, tocopherols, and other classes of phytochemicals with known or putative anti-influenza properties. I

SUBMITTER: Eliopoulos AG 

PROVIDER: S-EPMC9787935 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature